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Retinol Sandwiching: A St. Louis Dermatologist’s Guide


Retinol Sandwiching
Squeezing a small amount of retinol onto a fingertip for skincare application.

Retinol is one of the most powerful ingredients in dermatology, known for its ability to fight acne, reduce fine lines, and improve overall skin texture. However, many individuals experience irritation when using retinol, especially those with sensitive skin. This is where the "retinol sandwiching" method comes in—a technique that the dermatologists at Mid-County Dermatology in St. Louis counsel their patients on to help minimize irritation while still reaping the benefits of retinol. Read on to learn how to incorporate retinol sandwiching into your routine for clearer, healthier skin.


What Is Retinol Sandwiching?

Retinol sandwiching involves layering a moisturizer before and after applying retinol. This technique acts as a buffer, allowing your skin to adjust to retinol gradually while preventing excessive dryness and irritation. It’s an excellent strategy for individuals new to retinol or those with sensitive or acne-prone skin.


What Are The Benefits of Retinol Sandwiching

  • Reduces irritation and dryness

  • Allows gradual retinol absorption

  • Suitable for sensitive and acne-prone skin

  • Helps maintain the skin barrier while using retinol


Step-by-Step Guide to Retinol Sandwiching


Step 1: Cleanse Your Skin

Start with a gentle, hydrating cleanser to remove dirt, oil, and makeup. Avoid harsh exfoliants or active ingredients that may increase sensitivity.

Step 2: Apply a Light Moisturizer (First Layer)

Use a lightweight, non-comedogenic moisturizer like Cetaphil, CeraVe, or Vanicream moisturizing cream to create a barrier between your skin and retinol. This helps reduce potential irritation and dryness.

Step 3: Apply Retinol

Take a pea-sized amount of retinol and apply it evenly across your face, avoiding sensitive areas like the eyes, corners of the nose, and lips.

Step 4: Seal with a Second Layer of Moisturizer

Apply another thin layer of your moisturizer to lock in hydration and further buffer the retinol’s effects.

Step 5: Use Sunscreen in the Morning

Retinol can increase skin sensitivity to the sun. Always apply a broad-spectrum SPF 30 or higher during the day to protect your skin - CeraVe AM, Elta MD UV Clear, and La Roche Posay Melt-In Sunscreen Milk are personal favorites.


Best Products for Retinol Sandwiching

For St. Louis residents looking for dermatologist-approved skincare, consider the following products:

  • Gentle Cleansers: CeraVe Hydrating Cleanser, La Roche-Posay Toleriane Hydrating Gentle Cleanser, Cetaphil Cleanser

  • Moisturizers: Vanicream Moisturizing Cream, CeraVe Daily Moisturizing Lotion

  • Retinols: Differin (Adapalene), CeraVe Retinol Serum, Neutrogena Retinol SkinCeuticals Retinol 0.3, or prescription-strength options (tretinoin) from your dermatologist

  • Sunscreens: EltaMD UV Clear SPF 46, La Roche-Posay Anthelios Melt-In Sunscreen


Who Should Try Retinol Sandwiching?

This method is ideal for:

  • Retinol beginners

  • Those with dry or sensitive skin

  • Individuals with acne-prone skin


When to See a Dermatologist

If you experience persistent irritation, severe dryness, or worsening acne, it’s best to consult a board-certified dermatologist. At Mid-County Dermatology, we offer personalized skincare recommendations to help you achieve your skin goals safely and effectively.


Final Thoughts

Retinol sandwiching is a game-changer for those who want the benefits of retinol without the irritation. Whether you’re battling acne or looking for anti-aging solutions, this method can help you achieve smooth, healthy skin. If you’re in St. Louis and need expert dermatological care, schedule an appointment with Mid-County Dermatology today by calling or texting 314-994-0200 or schedule online!

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